A science note - HPS type II

I've been meaning to make note of this on the blog for a while now.

In the last few years we had updated our literature to reflect the findings that the pulmonary fibrosis of HPS only seemed to occur in types 1 and 4. I had been made aware of a case of a type II with pulmonary fibrosis, but it wasn't directly and I hadn't seen it documented in the literature.

This week, while checking for any new papers on HPS, I found one out of the UK. It was a case report on two non-related people with HPS type 2. They were children. One developed pulmonary fibrosis at 36 months of age.

We need to update our literature and the "Presentation in a Bag" to reflect this possibility.

HPS type II seems to be different than other forms as it involves a severely compromised immune system.

I'm not a scientist or a doctor, but I find that intriging. Am I misunderstanding that? Often problems related to pulmonary fibrosis are because our immune system in our lungs is swatting at flies with base ball bats, or so I had thought. Perhaps I misunderstood? More investigation needed.......

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